Methyl salicylate, nf 119368 me170 spectrum chemical. The odor is often described as minty due to its use in mint candies. Methyl salicylate material safety data sheet cas no 11936. Methylparaben is a 4hydroxybenzoate ester resulting from the formal condensation of the carboxy group of 4hydroxybenzoic acid with methanol. Refractive index of c8h8o3 methyl salicylate rheims. Methyl salicylate functions as a flavouring agent in chewing gums, syrups and ice creams.
It can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. Methyl salicylate, nf is used to treat minor aches and pains of the muscles and joints. Preparation of methyl salicylate, by darkblade48 heres a simple synthesis of methyl salicylate oil of wintergreen, for those that just started organic chemistry though of course, even if you are a bit more experienced, nothing beats a minty smelling. Alcohol reagent, 100% histology grade polysciences, inc. It has a role as a plant metabolite, an antimicrobial food.
It has counter irritant and antiinflammatory effects. Methyl salicylate type of posting revision bulletin. Methyl salicylate oil of wintergreen or wintergreen oil is an organic ester naturally produced by many species of plants, particularly wintergreens. Structurally, methyl salicylate is the methyl ester of salicylic acid, produced e. The information in this msds was obtained from current and reliable sources. A gas chromatographicmass spectrometric gcms assay was developed for the quantitative analysis of methyl salicylate mes, ethyl salicylate es and salicylic acid sa from biological fluids. Methyl salicylate appears as colorless yellowish or reddish liquid with odor of wintergreen. Methyl salicylate is found in trees, legumes and exotic plants. Methyl salicylate topical may be used up to 4 times daily or as directed on the medicine label. Involvement of transient receptor potential vanilloid subtype 1 in analgesic action of methyl salicylate.
Simultaneous quantitative analysis of methyl salicylate. Salicylate rs and 3gml of usp methyl salicylate re samples. Methyl salicylate is a topical analgesic, as is capsaicin and menthol. Sample solution and standard solution lated compound a rs in diluent calculate the percentage of each individual impurity in standard solution. S80082, s93305, nc9972460, o3695 500, o3695500, o3695500, xxo3695et500 synonyms. Methyl salicylate c8h8o3 cid 43 structure, chemical names, physical and chemical. If in scope, these drugs will include rxnorm normal forms when editing is. Fisher scientific 1 reagent lane fair lawn, nj 07410 for information, call. Remove the patch and apply a new patch 1 or 2 times daily if needed. Methanol is the alcohol which is released by hydrolysis. Another 5day bod determination yielded 65% of the theoretical bod3. As a natural oil, it is used all over, as an industrial compound it is somewhat dangerous because it gets on your skin and will inflame and make the area warm. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy.
Methyl salicylate is fully degradation biodegradable. Buy methyl salicylate cas 119368, an anticoagulant that interrupts the vitamin k1epoxide cycle, from santa cruz. It is the most frequently used antimicrobial preservative in cosmetics. To apply a methyl salicylate topical skin patch, remove the liner and apply the patch to your skin over the area of pain. Despite the common use of ms as a pain reliever, the. India veritas house, 70 mint road, fort, mumbai 400 001. The product itself and its products of degradation are not toxic. Material safety data sheet methyl acetate section 1 chemical product and company identification msds name. First aid measures always seek professional medical attention after first aid measures are provided. Methyl salicylate pesticide chemical code 076601 is the major constituent of oil of wintergreen which is a natural fragrant oil. Necessary reagents methanol, ch 3oh salicylic acid, ohc 6h 4cooh. Methyl salicylate, c 8 h 8 o 3 chemical formula c 6 h 4 hocooch 3 other names.
Spectrum chemical nf products are manufactured, packaged and stored under current good manufacturing practices cgmp per 21cfr part 211 in fda registered and inspected facilities. Methyl salicylate is readily absorbed and may have systemic effects if applied to large areas of the body. Esters react with acids to liberate heat along with alcohols and acids. The material safety data sheet msds for ms contains. Excessive, prolonged or repeated contact may give rise to skin irritation. Central drug house p ltd 728 vardaan house new delhi2 india. Monoclonal antibody trial size samples click here for a free sample. The product chemistry data requirements for methyl salicylate are fully satisfied.
Sds of methyl salicylate, safety data sheets, cas 119368. Application methyl salicylate has been used in the hyalinization of tissues for pulmonary angiography. The above information has been compiled from various sources and has the possibility of discrepancy and being outdated information. Burning cold, heat these sensations can all work together so that when we apply methyl salicylate containing creams, lotions, or ointments we feel a warming sensation. This structure is also available as a 2d mol file or as a computed 3d sd file the 3d structure may be viewed using java or javascript. Sigmaaldrich offers a number of methyl salicylate products. Methyl salicylate oil of wintergreen or wintergreen oil is an organic compound with the formula c 6 h 4 ohco 2 ch 3. Find patient medical information for methyl salicylate on webmd including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
Methyl salicylate was completely degraded by a microbial mixture when incubated for 7 days at 30\u00b0c4. Methyl salicylate is a colorless, yellowish or reddish, oily liquid with the odor and taste of wintergreen. To extend the capable of methyl salicylate, more investigation into other different analytes as well as complicated sample matrices e. Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and. It has a role as a flavouring agent, a metabolite and an insect attractant. First, the free carboxylic acid group will be produced when we hydrolyze the methyl salicylate. The compound was first extracted and isolated from plant species gaultheria procumbens in 1843. Numbing might follow depending on the concentration of methyl salicylate is applied. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Methyl salicylate has been used in the hyalinization of tissues for pulmonary angiography. Safety data sheet creation date 14jul2014 revision date 17jan2018 revision number 3 1.
The supplier identified below generated this sds using the ul sds template. It is a colorless, viscous liquid with a sweet fruity odor reminiscent of root beer. Safety data sheet according to 29cfr19101200 and ghs rev. It is a benzoate ester and a member of salicylates. This methyl salicylate msds sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. However the data is provided without any warranty, expressed or implied, regarding its correctness or accuracy. Our histology grade alcohol reagent is composed of 90 parts ethyl alcohol, 5 parts methyl alcohol and 5 parts isopropyl alcohol, vv blend. It occurs naturally in several fruits, particularly in blueberries. Methyl salicylate component 1420 mgkg oral rat health hazards, general. Methyl salicylate an ester can be hydrolyzed to produce salicylic acid. Salicylate 9, iii, marine pollutant not regulated disclaimer.
It can be also concluded that methyl salicylate is feasible to be used as an alternative extraction solvent. Preferred mixture for dehydrating tissue samples prior to embedding. The two different functional groups on the aromatic ring are utilized in this lab. Uses advised against not for food, drug, pesticide. Buy methyl salicylate cas 119368, an anticoagulant that interrupts the vitamin. Reregistration eligibility decision for methyl salicylate. Methyl salicylate cas no 119368 material safety data.
If seeking medical attention, provide sds document to physician. Identification product name methyl salicylate reagent cat no. We offer halal and kosher methyl salicylate made in an iso9001, iso22000 fssc22000 and cgmp certified facility. Use of methyl salicylates as a trialing chemical agent. Methyl salicylate in a five day bod test exhibited a value of 5557% of the theoretical bod1,2. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database.